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WEI Shengnan

Ph.D. student at the University of Macau. Co-founder of MacOrigen Technology Limited.

Macau SAR, China; Hengqin, Guangdong, China

About Me

Welcome to my website!

I am a biomedical engineer specialized in tissue engineering and regenerative medicine.

My work mainly involved biomaterials and stem cells. With a multidisciplinary background, I also carried out experiments about finite element analysis and biomanufacturing as well. Currently, I focused on early fate determination of human pluripotent stem cells (PSCs) and the immunomodulatory properties and quality control of mesenchymal stem or stromal cells (MSCs).

Education

Aug. 2022 – Present
The University of Macau
Macau SAR, China
Ph.D. student in Biomedical Sciences
Aug. 2020 – Feb. 2022
The University of Sydney
NSW, Australia
M.Eng. in Biomedical Engineering
Aug. 2016 – Jul. 2020
Beijing University of Chemical Technology
Beijing, China
B.Eng. in Biomedical Engineering

Research

  • Pluripotent stem cell fate regulation and definitive endoderm differentiation.
  • MSC immunomodulation & quality control
  • Tissue-engineering-oriented applications of biomaterials.
  • Finite element analysis to investigate micro- and macro-scopic biomechanics and biophysics.

Find detials on my Research page.

Work Experience

Jul. 2024 – Present
MacOrigen Technology Limited (Macau)
Macau SAR, China
Co-founder
  • Designed, conducted, and interpreted experiments, leading the development of a defined MSC medium as part of strategic R&D initiatives.
  • Facilitated collaboration with the university.
  • Participated in preparation and presentation at various exhibitions, including Macao International Trade and Investment Fair (MIF), enhancing brand visibility and impact.

Publications

  • Y. Meng, C. Deng, X. Xiao, S. Wei, C. Song, J. Wang, C. L. Lei, W. Liu, G. Chen, The modulation of calcium and chloride channels induces cardiomyocytes from human pluripotent stem cells. Int. J. Biol. Sci. 2025; 21(1): 95-108
    [Access]
  • Z. Li, W. Li, S. Wei, Q. Zhu, Genetic engineering bacterium for simultaneously producing glycolic acid and lactic acid as well as construction method and application of genetic engineering bacterium, China Patent CN109337848A, 2019

Conference Presentations

  • S. Wei, Designing Fully Defined Platforms that Enable MSC Expansion and Functional Characterization, Oral Presentation, 10th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Apr. 2026
  • S. Wei, Z. Zhang, Y. Chen, T. Sun, L. Li, G. Chen, Chemically Defined Platform for Standardised Culture and Immunomodulatory Evaluation of Human MSCs, Poster, Singapore Cell and Gene Therapy (SCGT) Pan Asia Summit 2025, Jul. 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 11th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 4th International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM), May 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 9th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Mar. 2025
  • S. Wei, G. Chen, Signalling Pathways During the Journey Towards Definitive Endoderm: Those Who Can and Those Who Cannot, Poster, 10th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2024
  • S. Wei, G. Chen, Signalling Pathways During the Journey Towards Definitive Endoderm: Those Who Can and Those Who Cannot, Poster, 8th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Mar. 2024
  • S. Wei, Z. Zhang, G. Chen, "Qualitative analysis of hPSC colony mechanics with finite element method", Poster, 9th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2023
  • S. Wei, A. Entezari, "Design optimization of total knee arthroplasty prostheses: an FEA study", Poster, 7th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Apr. 2023
  • S. Wei, Z. Zhang, G. Chen, "Qualitative analysis of hPSC colony mechanics with finite element analysis", Poster, 2nd International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM), Apr. 2023
  • S. Wei, A. Entezari, "Design optimization of total knee arthroplasty prostheses: an FEA study", Poster, 8th Macau Symposium on Biomedical Sciences (MSBS), Oct. 2022

Awards

  • Apr 2026 – First Prize for Oral Presentation, 10th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants
  • Aug. 2025 – Second Place of 2025 University of Macau & Bank of China Trophy UltiMater Entrepreneurship Competition
  • May 2025 – Third Prize for Excellent Poster at the 4th International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM)
  • Mar. 2025 – Outstanding Poster (First Prize) at the 9th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants
  • Sept. 2019 – Best Intern in the Advanced Practicum at China-Japan Friendship Hospital

Contacts