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WEI Shengnan

Ph.D. student at the University of Macau. Co-founder of MacOrigen Technology Limited.

Macau SAR, China; Hengqin, Guangdong, China

About Me

Welcome to my website!

I am a biomedical engineer specialized in tissue engineering and regenerative medicine.

My work mainly involved biomaterials and stem cells. With a multidisciplinary background, I also carried out experiments about finite element analysis and biomanufacturing as well. Currently, I focused on early fate determination of human pluripotent stem cells (PSCs) and the immunomodulatory properties and quality control of mesenchymal stem or stromal cells (MSCs).

Education

Aug. 2022 –Present
The University of Macau
Macau SAR, China
Ph.D. student in Biomedical Sciences
Aug. 2020 –Feb. 2022
The University of Sydney
NSW, Australia
M.Eng. in Biomedical Engineering
Aug. 2016 –Jul. 2020
Beijing University of Chemical Technology
Beijing, China
B.Eng. in Biomedical Engineering

Research

  • Pluripotent stem cell fate regulation and definitive endoderm differentiation.
  • MSC immunomodulation & quality control
  • Tissue-engineering-oriented applications of biomaterials.
  • Finite element analysis to investigate micro- and macro-scopic biomechanics and biophysics.

Find detials on my Research page.

Work Experience

Jul. 2024 –Present
MacOrigen Technology Limited (Macau)
Macau SAR, China
Co-founder
  • Designed, conducted, and interpreted experiments, leading the development of a defined MSC medium as part of strategic R&D initiatives.
  • Facilitated collaboration with the university.
  • Participated in preparation and presentation at various exhibitions, including Macao International Trade and Investment Fair (MIF), enhancing brand visibility and impact.

Academic Experience

  • Teaching Assistant, University of Macau
    • GEST1002 Quantitative Reasoning for Social Science (2022)
    • HSCI8005 Critical Scientific Reading-Writing and Analysis (2024)

Publications

Papers
  • Y. Meng, C. Deng, X. Xiao, S. Wei, C. Song, J. Wang, C. L. Lei, W. Liu, G. Chen. The modulation of calcium and chloride channels induces cardiomyocytes from human pluripotent stem cells. Int. J. Biol. Sci. 2025; 21(1): 95–108 [Access]
Patents
  • W. Liu, G. Chen, S. Wei. A cell culture medium supplement, its preparation method and application. China Patent CN121538155A, 2026 [Access]
  • Z. Li, W. Li, S. Wei, Q. Zhu. Genetic engineering bacterium for simultaneously producing glycolic acid and lactic acid as well as construction method and application of genetic engineering bacterium. China Patent CN109337848A, 2019 [Access]

Conference Presentations

  • S. Wei, Z. Zhang, Y. Chen, T. Sun, L. Li, G. Chen, Chemically Defined Platform for Standardised Culture and Immunomodulatory Evaluation of Human MSCs, Poster, 12th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2026
  • S. Wei, Z. Zhang, Y. Chen, T. Sun, L. Li, G. Chen, Chemically Defined Platform for Standardised Culture and Immunomodulatory Evaluation of Human MSCs, Poster, 5th International Conference of the Guangdong-Hong Kong-Macau Greater Bay on Regenerative Medicine, Apr. 2026
  • S. Wei, Designing Fully Defined Platforms that Enable MSC Expansion and Functional Characterization, Oral Presentation, 10th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Apr. 2026
  • S. Wei, Z. Zhang, Y. Chen, T. Sun, L. Li, G. Chen, Chemically Defined Platform for Standardised Culture and Immunomodulatory Evaluation of Human MSCs, Poster, Singapore Cell and Gene Therapy (SCGT) Pan Asia Summit 2025, Jul. 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 11th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 4th International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM), May 2025
  • S. Wei, Z. Zhang, G. Chen, Finite Element Analysis of hPSC Colony Mechanics: From Single Cells to Colonies, Poster, 9th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Mar. 2025
  • S. Wei, G. Chen, Signalling Pathways During the Journey Towards Definitive Endoderm: Those Who Can and Those Who Cannot, Poster, 10th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2024
  • S. Wei, G. Chen, Signalling Pathways During the Journey Towards Definitive Endoderm: Those Who Can and Those Who Cannot, Poster, 8th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Mar. 2024
  • S. Wei, Z. Zhang, G. Chen, "Qualitative analysis of hPSC colony mechanics with finite element method", Poster, 9th Macau Symposium on Biomedical Sciences (MSBS), Jun. 2023
  • S. Wei, A. Entezari, "Design optimization of total knee arthroplasty prostheses: an FEA study", Poster, 7th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants, Apr. 2023
  • S. Wei, Z. Zhang, G. Chen, "Qualitative analysis of hPSC colony mechanics with finite element analysis", Poster, 2nd International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM), Apr. 2023
  • S. Wei, A. Entezari, "Design optimization of total knee arthroplasty prostheses: an FEA study", Poster, 8th Macau Symposium on Biomedical Sciences (MSBS), Oct. 2022

Awards

  • Apr. 2026 –First Prize for Oral Presentation, 10th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants
  • Aug. 2025 –Second Place of 2025 University of Macau & Bank of China Trophy UltiMater Entrepreneurship Competition
  • May 2025 –Third Prize for Excellent Poster at the 4th International Guangdong-Hong Kong-Macau Greater Bay Area Conference in Regenerative Medicine (GBRM)
  • Mar. 2025 –Outstanding Poster (First Prize) at the 9th Symposium on Biomedical Sciences for Students, Postdoctoral Fellows and Research Assistants
  • Sept. 2019 –Best Intern in the Advanced Practicum at China-Japan Friendship Hospital

Contacts